The Impact of Elexacaftor/Tezacaftor/Ivacaftor on Fat-Soluble Vitamin Status and Supplementation in a Pediatric Cystic Fibrosis Cohort

This study found following ETI initiation vitamin D levels increased, and the requirement for fat-soluble vitamin supplementation appeared to decrease. Whilst ETI was not associated with increased Vitamin A and E, the burden of supplementation decreased, and Vitamin A supplementation maybe more effective.